Human Chromosome
8 Homepage
The University of Houston, September 2003
 [for Professionals mainly]
This page is an attempt consolidate
information and resources on the physical and genetic mapping of human
chromosome 8, as well as information on chromosome 8 specific genetic diseases
current of interest to my research group ...
Cytogenetic
and molecular evidence of constitutional mosaic trisomy 8 ... in a phenotypically
normal woman
J. Meck et al.
[for Professionals mainly]
As a constitutional abnormality the phenotype ranges
from normal to severe. Trisomy 8 is also an acquired chromosome abnormality
common in myeloid disorders ...
+8
or trisomy 8 and related diseases
Atlas of Genetics and Cytogenetics in Oncology and Haematology, November 1998
[for Professionals mainly]
Chronic myelogenous leukaemia (CML) ... +8 has apparently no prognostic
significance in CML ... other chronic myeloproliferative diseases : polycytemia
vera (PV), and idiopathic myelofibrosis (but not found in essential thrombocythemia) ... +8 is found in 20% of PV cases with an abnormal karyotype ...
National Parent to
Parent Network
Julie J. Gordon, MUMS National Parent to Parent Network, May 21, 2007
[Support Groups]
What is Parent-to-Parent Matching?... MUMS Data Base List of Disorders
...
Chromosome
and Genetic Links
TrisomyOnline.org, April 6, 2001
[Support Groups]
General Information, Chromosome and Genetic web sites ...
Unique, Rare
Chromosome Disorder Support Group
Unique - The Rare
Chromosome Disorder Support Group, October 12, 2007
[Support Groups]
A source of information, mutual support and self-help to families of
children with any rare chromosome disorders including deletions, trisomy,
balanced translocations ...
Canadian
Directory of Genetic Support Groups
London Health Sciences Centre, February 14, 2004
[Support Groups]
Canadian Association of Genetic Counsellors ... June 30, 1998
...
Chromosome
8 trisomy syndrome
Stanley Jablonski, December 12, 2006
Multiple Congenital Anomaly/Mental Retardation (MCA/MR) Syndromes.
National Library of Medicine. Trisomy of chromosome 8 with retarded psychomotor
development, long and narrow trunk, dysmorphic facies with blank expression,
musculoskeletal defects, eye anomalies, and visceral and other abnormalities
... Head and neck: Expressionless facies, micrognathia, and prominent forehead
... Mouth and oral structures: Everted lips, highly arched or cleft palate,
and stretched
lingual frenulum ... Cardiovascular system: Septal defects and great
vessel anomalies ... Growth and development: Speech, moderate mental, and
occasional growth retardation ...
Langer-Giedion Syndrome
I.B.I.S. Birth Defects, November 26, 2002
[Ukrainian]
A fact sheet for specialists in Ukrainian.
Main diagnostic criteria ... Etiology ... Clinical features ... Associated anomalies ... Differential diagnosis ... Prognosis ... OMIM number ...
Chromosome 8 Trisomy
I.B.I.S. Birth Defects, May 2, 2003
[Ukrainian]
A fact sheet for specialists in Ukrainian.
Synonyms ... Main clinical features and symptoms... Associated anomalies ... Prevalence ... Diagnosis ... Prognosis ...
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Last Updated: 2007/10/12
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